U have to be able to throw 1 down at the end of ur hand. But u might get caught out by someone else doing the same. or 3 or 4 of a kind so u don't get caught with those high scoring cards or hold em and try and catch everyone else out with more cards/points. or 3 or 4 of a kind or put them down when u have like 10,J,Q. You can either keep all your cards in your hand, even when you have 4,5,6. And the main point is not to get caught with cards in your hand, especially high number cards, because the card numbers are all added up for the losers and taken off their 101, the player with points at end of game wins. Then from there on each player picks a card from deck, keeps what they think will give them a winning hand then puts one out in centre pile etc etc.
Dealer starts by discarding a card they think they hope they don't need.
The 101 my Granda showed us started with everyone having 101 points, and was like gin rummy,everyone is dealt 7 cards, the dealer 8, dealer changes each completed hand passing round the players clockwise or anti-clockwise -doesn't matter.